Unlike other galleries, you can’t submit your site to Most Inspired.
To appear on Most Inspired you must first be selected to appear on other design galleries.
Most Inspired collects the featured sites from those galleries and builds an uberlist of great looking sites.
If you’re looking for some places to submit your site, check out the gallery list, and we also recommend submitting your site to Cool Site Collection. Cool Site Collection is a Most Inspired partner site where the users submit and vote on which sites should be featured.